Cochlear imaging

We are developing optical imaging techniques for the diagnosis of hearing loss due to deterioration of the cochlea. The small size of the cochlea and the thick bone surrounding it place challenging obstacles for producing cochlear images in humans. We are developing endsoscopes and ablation instruments that can reach the cochlea through the middle ear and produce images of the cells in the cochlea, ablate bone, and deliver medications.

 

Collaborators:

Professor Konstantina Stancovic, Harvard Medical School 

 

Publications:

 

  1. Surgical anatomy of the human round window region: implication for cochlear endoscopy through the external auditory canal; Takeshi Fujita, Jung E. Shin, MaryBeth Cunnane, Kyoko Fujita, Simon Henein, Demetri Psaltis, Konstantina M. Stankovic, Otology & Neurology, 1 (2016)
  2. Human audiometric thresholds do not predict specific cellular damage in the inner ear; Lukas D. Landegger, Demetri Psaltis, Konstantina M. Stankovic, Hearing Research, Vol 335, 83-93 (2016) 
  3. In situ imaging of the mouse cochlea using two-photon microscopyXin Yang, Ye Pu, Demetri Psaltis, Konstantina M. Stankovic, SPIE Proceedings (2013) –  (pdf)
  4. Two photon microscopy of the mouse cochlea in situ for cellular diagnosis; Xin Yang, Ye Pu, Chia-Lung Hsieh, Cheng Ai Ong, Demetri Psaltis, Konstantina M. Stankovic; Journal of Biomedical Optics, Vol. 18, Issue 3, Art. 031104 (2013) – (pdf)

Others :

Optical Imaging : https://vimeo.com/user10379912/review/208821603/aca5bfd07

Click here to view the Poster.